Spastic paraplegia four (SPG4; also known as SPAST-HSP) is characterized by insidiously progressive bilateral lower-limb gait spasticity. A lot more than fifty% of impacted people today have some weakness from the legs and impaired vibration sense within the ankles.안전하고 신뢰할 수 있는 정보: 검증된 정보만 제공하여 안심하